V H ‐V L interdomain dynamics observed by computer simulations and NMR
نویسندگان
چکیده
منابع مشابه
Interdomain dynamics explored by paramagnetic NMR.
An ensemble-based approach is presented to explore the conformational space sampled by a multidomain protein showing moderate interdomain dynamics in terms of translational and rotational motions. The strategy was applied on a complex of calmodulin (CaM) with the IQ-recognition motif from the voltage-gated calcium channel Ca(v)1.2 (IQ), which adopts three different interdomain orientations in t...
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ژورنال
عنوان ژورنال: Proteins: Structure, Function, and Bioinformatics
سال: 2020
ISSN: 0887-3585,1097-0134
DOI: 10.1002/prot.25872